CORC Filovirus strategic review meeting on Bundibugyo Virus Disease (BDBV) research

24 September 2026 13:30 – 15:45 CET
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The Filovirus Collaborative Open Research Consortium (CORC), co-convened by WHO, Africa CDC and ANRS MIE/Inserm, brings together researchers, public health authorities, clinical investigators, regulatory agencies, funders and operational partners to accelerate evidence generation and research coordination during filovirus outbreaks.

In light of the ongoing Bundibugyo virus disease (BDBV) outbreak in the Democratic Republic of the Congo, a virtual meeting was held on 24 September 2026 with an aim of providing an updated overview of the epidemiological situation and ongoing research efforts, while facilitating coordination across therapeutic, post-exposure prophylaxis (PEP), vaccine development and clinical trial activities. The meeting offered an opportunity to discuss key scientific, regulatory and operational challenges, identify research priorities, and explore opportunities to accelerate evidence generation to inform outbreak response and preparedness.

The recording of the sesison proceedings can be accessed here:  CORC Filovirus strategic review meeting on BDBV.

Presentations

Epidemiological update: current dynamics of the BDBV outbreak, geographical spread, transmission chains and surveillance data by Steve Ahuka (National Incident Manager / INRB)

EBO-PEP: recruitment and operational experience - next steps by Jepsy Yango (INRB) Marie Jaspard (INSERM)

Bundibugyo virus vaccines clinical development ​- AMA-EMA considerations by Marco Cavaleri (European Medicines Agency)

Tumaini Tiral: Phase 2/3 study design by Hugo Kavunga (INRB)

Recent Animal Data using rVSVΔG-ZEBOV-GP vaccine (ERVEBO) against Bundibugyo virus (BDBV) by Axel Lehrer (University of Hawaii)

SAGE recommendations by Kate O'Brien (WHO SAGE)

Technical Advisory Group on Candidate Vaccines Prioritization (TAG-CVP), by Mike Levine (University of Maryland School of Medicine)

AREBO-BUDSEV: Multiplex Filovirus Serology to Characterize Humoral Immunity, Improve Exposure Classification, and Assess Cross-Reactive Vaccine Responses During the Bundibugyo Virus Disease Outbreak in the Democratic Republic of the Congo by Antoine Nkuba (IRD)