Measles
A WHO Surveillance Immunization Medical Officer engaging with once-unreached communities in Gopalgung District as part of the mation-wide emergency measles-rubella vaccination campaign.
Measles is a highly contagious viral disease caused by the measles virus. It spreads through the air by respiratory droplets and aerosols when an infected person coughs or sneezes. Symptoms include high fever, cough, runny nose, red eyes and a characteristic generalized rash.
Measles can occur at any age in people who are not immune but is most common and most severe in young children. Complications include ear infections, diarrhoea, pneumonia, encephalitis and blindness, and can lead to death. Disease and complications are more frequent and often more severe in malnourished children and in people who are immunocompromised. Because measles is so transmissible, population immunity of about 95% with two doses is needed to prevent outbreaks.
Measles vaccines
Live-attenuated measles vaccines are safe, effective and inexpensive, and have been in use since the 1960s. They are available as monovalent vaccines or in combination with rubella (MR), mumps and rubella (MMR), or mumps, rubella and varicella (MMRV) vaccines, and are referred to collectively as measles-containing vaccines (MCV).
WHO’s recommendations for the use
- WHO recommends that all countries include two doses of measles-containing vaccine in their routine immunization schedules.
- Countries should aim to reach and maintain at least 95% coverage with both doses in every district to achieve and sustain measles elimination.
- Where routine coverage is insufficient, supplementary immunization activities (SIAs) should be used to reach children who have not been vaccinated or who have received only one dose.
- Countries should strengthen surveillance to detect outbreaks early and respond rapidly with vaccination.
Vaccine schedule
- The first dose (MCV1) should be given at 9 months of age in countries with ongoing measles transmission and a high risk of measles death among infants. In countries with low risk of transmission, MCV1 can be given at 12 months of age.
- The second dose (MCV2) should be given in the second year of life, at 15–18 months of age, or at school entry in countries with very low transmission and high coverage. The minimum interval between doses is 4 weeks.
- Countries do not need to meet previous coverage criteria before introducing a routine second dose.
- Children and adults who have not received two doses should be vaccinated to complete the schedule.
WHO position paper
Publications
Targeted and selective strategies in measles and rubella vaccination campaigns: Interim guidance
The World Health Organization provides regional and national strategies and operational plans that aim to support countries in work to achieve measles...
Meeting of the Immunization and Vaccine-related Implementation Research Advisory Committee (IVIR-AC), September...
The IVIR-AC recommendations are based on technical discussions during a hybrid (in-person/virtual) meeting of the IVIR-AC, held on 12–14 September...
Measles Outbreak Guide
The conclusions of the Global Measles and Rubella Strategic Plan 2012–2020 implementation midterm review highlighted the need to update protocols...
Measles vaccination status
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